Highlight selected keywords in the article text. Race to find. Lianhua Qingwen combined with conventional drugs may be a promising therapy for treating common pneumonia and COVID-19 pneumonia. Announcement of the national health and Health Commission of the people's Republic of China [EB /OL] (2020-01-20) [20200217]. Avoid alcohol and tobacco and spicy,cold, greasy food during taking this product. There are an increasing number of studies on for COVID-19 published with inconclusive results in recent. LHQW is not approved by Singapore's HSA for the prevention and treatment of Covid-19. Children should take under the supervision of adult. In accordance with the usage and dosage,the product should not be long term used. The Chinese medicine compound Lianhua Qingwen has been listed as the recommended drug for the diagnosis and treatment of respiratory infectious diseases by the national Wei Jian administration and the State Administration of traditional Chinese medicine for 20 times. In addition, only studies published in English and Chinese will be searched and included because of language barriers, so a language bias may exist. To consume within 2 weeks after opening. Chinese Journal of experimental pharmacology 2015;21:13943. CT images of patient Mr. Lin (Male, Fifty-five years old) during different treatment periods. Meanwhile, China also provides technical solutions through long-distance video exchanges to share treatment experience with Japan, South Korea, Italy, the United States, Iran, Singapore, and so on. The composition of Lianhua Qingwen granules is consistent with the pathogenesis of the disease. It has a wide-spectrum antiviral, effective antibacterial, antipyretic and anti-inflammatory, antitussive and expectorant, immune-regulating and other systemic intervention functions,[1625] especially for the coronavirus SARS[26] And Middle East respiratory syndrome (MERS)[27] have significant inhibitory and killing effects. Just because a supplement is derived from natural sources does not mean it is safe. All relevant data are within the article and its supporting information files. Recently, the novel coronavirus pneumonia (COVID-19) epidemic has spread continuously and has been classified as class B infectious diseases (class a management). Results: 2018;Beijing: Science and Technology Literature Press, 13271329. > 5 to <12 years old: 2 to 3 capsules x 3 times a day ( after breakfast, lunch and dinner). Part of the goods frequent replacement of packaging, such as goods and pictures are not exactly the same, please refer to the goods you receive. Buy Articles in Google Scholar by Xiaolin Zhang, MD, Other articles in this journal by Xiaolin Zhang, MD, Intermediate dose cytarabine improves survival and relapse-free rate compared with standard-dose cytarabine as post-remission treatment for acute myeloid leukemia: A retrospection study, Privacy Policy (Updated December 15, 2022). An official website of the United States government. 1. Placebo, routine western medicine therapy, and other therapeutic methods in the comparators (drugs, dose, frequency, duration); (5) Outcomes: the primary outcomes include total efficiency, primary symptoms, and Nevertheless, this systematic view should help further expand our understanding of Lianhua Qingwen combined with conventional antiviral Western Medicine treatments in COVID-19 and asymptomatic infection. Do not give during pregnancy & lactation, & in childn. This product should not be used in treatment of wind-cold. It cannot be bought over-the-counter and not recommended for self-medication. LHQW won the 2nd prize of the National Scientific and Technological Progress Award in 2011 for the treatment of influenza. Wu Yiling. High-tech Demonstration Project of National Development and Reform Commission 13. The data extraction form will include the following items: Two reviewers/authors (ZXL and ZQ) will independently evaluate the quality of the included trials through assessing the risk of bias using the following tools, when appropriate: The following aspects of included trials will be assessed: sequence generation, allocation concealment, blinding of participants, personnel and outcome assessors, incomplete outcome data, and selective outcome reporting. Novel coronavirus pneumonia treatment plan issued by the national health and Health Committee, State Administration of traditional Chinese medicine (trial version sixth) [EB/OL]. Early Treatment>14 years & above:4capsules x 3 times a day ( after breakfast, lunch and dinner) for7 to 10 days. For novel coronavirus pneumonia, the total effective rate of TCM is over 90%.[EB/OL]. For oral use after meals,4 capsules thrice daily or by medical ordor5 boxes for a treatment course. sharing sensitive information, make sure youre on a federal [2]. [25]. The authors have no conflicts of interest to disclose. Is there any notice for taking Lianhua Qingwen Capsules? You may search for similar articles that contain these same keywords or you may Not suitable for long-term use. We plan to carry out the following subgroup analyses if possible: the study area is different, the average course of disease is different, and the length of treatment is different. If I2 test 50%, a random-effects model will be used for data analysis instead. Product PackingEach box contains 24 capsules in blister packing. Asia's one-stop resource for medical news, clinical reference and education, Click to view Lianhua Qingwen detailed prescribing information. Please try again soon. The assessment will be adjudicated into 4 levels: high, moderate, low, or very low. Lianhua Qingwen Capsules can significantly improve the total effective rate for COVID-19 patients, as well as shorten the hospital stay and treatment time, which is worth of promotion in the clinic. 4.Patients with diabetes patients,high blood pressure, heart diseases, liver disease, kidney disease and other severe chronic diseases shall take medicine under guidance of physician. Avoid receiving nourishing Chinese medicine during the period in this product. New Chinese medicine and clinical pharmacology 2007;18:69. Max: 7 days. Medicine. BackgroundLHQW's formulation is based on two ancient formulae from the Han and Qing dynasties - Maxing Shigan decoction and Yinqiao powder - following the SARS epidemic. 8600 Rockville Pike Chest radiographs. XLZ conceived of the study, and perform this review. National Library of Medicine Your message has been successfully sent to your colleague. In WANFANG, novel coronavirus pneumonia, 2019-nCOV, COVID-19, and SARS-COV-2 were first searched for the keywords, then searched for the theme word Lianhua Qingwen and Lianhua Qingke. The 2 search were merged with the relationship. Novel coronavirus pneumonia is being set up by CNKI for the new research project. It was created on the basis of establishing the treatment method of clearing away plague and detoxification, releasing lung and heat.[33] Based on treatise on Maxingshigan Decoction of Febrile Diseases and yinqiao powder of Differentiation of febrile diseases,, the prescriptions are composed to protect Qi and treat together, promote lung, and relieve heat. WebChronic obstructive pulmonary disease (COPD) is characterized by a chronic inflammatory response that is worsened by acute exacerbations. Below dosage is a guide only. [21]. BMC Complement Altern Med 2017;17:130. In 2012, Prevention and Treatment Scheme of Traditional Chinese Medicine for Type B Influenza, issued by the State Administration of Traditional Chinese Medicine The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2022 Aug 19;27(16):5292. doi: 10.3390/molecules27165292. Please enable scripts and reload this page. In 2015, Diagnosis and Treatment Scheme for Cases Infected with Middle East Respiratory Syndrome (MERS) (2015), issued by the National Health and Family Planning Commission Chinese herbal medicine 2008;31:12303. Should not be used for wind-cold common cold. While it has been included in the standard treatment for coronavirus patients in China, it faces hurdles in the West where scientists raise questions over the evidence and effectiveness of traditional medicine. The registered Chinese capsule Lianhua Qingwen that has been approved should have the FDAs labeling requirements written in English, Domingo said. In comparison with the control group, 1) the total effective rate was significantly higher in the observation group (P<0.05); 2) the disappearance rates of fever, cough and fatigue were statistically higher in the observation group; 3) the treatment time was significantly shorter and patient recovery was significantly better in the observation group; 4) the laboratory index levels [white blood cell (WBC), interleukin-6 (IL-6), serum amyloid A (SAA)] were better in the observation group. Shunya Zhu, Xiaoying Li, Yunling Wei, et al. [26]. Medicine (Baltimore). Ephedrine isanamphetamine-like compound, which is an addictive stimulant of the central nervous system. Copyright Shijiazhuang Yiling Pharmaceutical Co,Ltd. Therefore, the completeness of the evidence is not yet available. In 2010, Diagnosis and Treatment Scheme for Wind-warm Lung-heat Disease (Non-severe Community Acquired Pneumonia) (2010), issued by the Chinese Health Protection Committee and the State Administration of Traditional Chinese Medicine [30] The I2 statistic of <50% indicates a low level of statistical heterogeneity, and that of 50% will be considered substantial statistical heterogeneity. and transmitted securely. For oral use after meals,4 capsules one time and thrice daily. Forsythiae Fructus, Lonicerae Japonicae Flos, Ephedrae Herba (processed with honey), Armeniacae Semen Amarum (stir-baked), Gypsum Fibrosum, Isatidis Radix, Dryopteridis Crassirhizomatis Rhizoma, Houttuyniae Herba, Pogostemonis Herba, Rhei Radix et Rhizoma, Rhodiolae Crenulatae Radix et Rhizoma, l-Menthol, Glycyrrhizae Radix et Rhizoma. Teresa May Bandiola is a licensed pharmacist, a published writer, and a university instructor. 9 Experimental research also showed that LH exerted broad-spectrum effects on a series of influenza viruses by inhibiting viral propagation and regulating immune function. The rate of positive nucleic acid detection of COVID-19 from intranasal and pharyngeal swabs was significantly lower in the treatment group The treatment of influenza using the TCM patent product Lianhua Qingwen won the Second-class Prize of the National Science and Technology Progress Award in 2011. 10 [18]. For NRIs, evaluate its methodological quality with the Newcastle Ottawa scale (NOS). Receive exclusive coupons and special offers directly to your email inbox. WebFor patients showing mild symptoms, Lianhua Qingwen would be more effective. Clinical observation shows that the total effective rate of traditional Chinese medicine is >90%.[15]. The following electronic bibliographic databases will be searched to identify relevant studies: CNKI, CBM, VIP and Wanfang databases, PubMed, EMBASE, MEDLINE, Cochrane central, and clinical trial registration centers, such as China Clinical Trial Registration Center (ChiCTR), Netherlands National Trial Registration Center (NTR) and clinical trials.gov. [36]. Avoid spicy & greasy food during medication. 5.Children, preganant or lactation women,elderly ,feeble and weak patients ,spleen and stomach weakness patients should be taken under the guidance of physician. All review authors critically reviewed, revised and approved the subsequent and final version of the protocol. All data generated or analyzed during this study are included in this published article [and its supplementary information files]. The Potential of Ameliorating COVID-19 and Sequelae From. Lianhua Qingwen, which was approved by China Food and Drug Administration (CFDA) in 2004, was the first traditional Chinese medicine that entered the rapid drug approval channel of the CFDA and was used to prevent severe acute respiratory syndrome (SARS). We will judge the each domain as low risk of bias, high risk of bias," or uncertain risk of bias" according to Higgins (2011), and pay particular attention to the risk of bias of cluster-randomised trials. TheChinese researchers also claim thatLHQWisa classical Chinese medical preparation and that itscapsules or granulesareconsist of 11 herbs, gypsum,and mentholwhich are recorded in the2015 Edition ofthe ChinesePharmacopoeia. Go and see the doctor if the symptom is not alleviated 3 days after administration. However, this systematic review will have some limitations. It has a history of abuse by athletes due to its ability to increase energy and alertness and help weight loss. (Photo by WANG ZHAO / AFP). [Main Ingredients] 4. patients: total number and number in both groups, baseline characteristics, diagnostic criteria, withdrawals, and losses to follow-up (reasons, description); 5. outcomes: outcomes specified above, adverse drug reactions, and adverse time, length of follow-up, quality of reporting of outcomes. For the treatment, the main effects of Lianhua Qingwen Jiaonang capsuleare as follows: First, after taking the capsule, patients' symptoms improve quickly, recovery rate up to 91.5%, conversion to severe cases down to 2.1%. [4]. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. [20]. It is compatible with Rhodiola to clear lung and remove blood stasis. Experimental study of Lianhuaqingwen capsule against influenza A virus in vitro [J]. A few patients have cough, expectoration, chest distress, dyspnea, muscle ache, diarrhea, and other symptoms. J Integr Med. - China reported 11 new infections of the coronavirus on March 14, and for the first time since the start of the epidemic the majority of them were imported cases from overseas. The capsule was earlier developed in 2003 to treat the severe acute respiratory syndrome (SARS) and extracts the essence of 13 herbs. For the treatment of COVID-19, the main effects of Lianhua Qingwen are as follows: First, after taking the capsule, patients' symptoms improve quickly, two days earlier than the control group. Second, CT scan result also shows that patients recover faster than the control group. Third, the capsule can shorten fever time. Holshue ML, DeBolt C, Lindquist S, et al. Wang DC, Yu M, Xie WX, Huang LY, Wei J, Lei YH. Clinically, Lianhua Qingwen Capsule can be used in the treatment of cold, flu-induced bronchitis, pneumonia, COPD, interstitial pneumonia and other lung inflammation. A: CT at admission (February 14, 2020); B: CT Reexamination after treatment (February 25, 2020); C: CT Reexamination after treatment (March 13, 2020); D: CT Reexamination after discharge (June 11, 2020). In addition, we learned from the experience of Rhubarb in the treatise on Febrile Diseases in the treatment of epidemic diseases. Add your comment to start the conversation. Common side effects are heart palpitations, nausea, and vomiting. Web[Administration and Dosage] For oral administration, 4 capsules once, 3 times a day. National Bureau of disease control and prevention. All randomized controlled trials (RCTs), Retrospective cohort study (RCSs), Comparison before and after the study (BAs) of Lianhua Qingwen combined with Conventional antiviral Western Medicine for COVID-19 will be included. Bioinform Biol Insights. [1014] Data showed that novel coronavirus pneumonia was confirmed in China, and 74,187 people used Chinese medicine, accounting for 91.5%, of which 61,449 in Hubei Province used Chinese medicine, accounting for 90.6%. First case of 2019 novel coronavirus in the United States. Manufacture address: No.238 Tianshan street, New and high development area, Shijiazhuang, Hebei, China. [Storage]Preserve in tightly closed containers, stored in a cool and dry place (20). Preliminary study on the inhibitory effect of three traditional Chinese medicine prescriptions on SARS related coronavirus in vitro [J]. All tests are 2-tailed, and P < .05 is considered statistically significant. BMJ 2008;336:9246. Even Wolters Kluwer Health Data curation: Xiaolin Zhang, Di Cao, Qi Zhang, Junnan Liu. [15]. The course of treatment is 7-10 days for patients with mild and moderate COVID-19. Also,its packaging is in Chinese characters and needs to comply with FDAs labeling requirements written in English.

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